Constipation is one of the most prevalent gastrointestinal complaints among middle-aged and older adults in China. Epidemiological data indicate that the prevalence of chronic constipation reaches 15%–20% in individuals aged 60 and above—and rises further in those over 80. Women are disproportionately affected compared with men. Many older adults experience persistent difficulty with bowel movements, prompting growing interest in gentle, long-term management strategies. A frequently asked question is whether Koyan Capsules—a widely recognized health supplement—are appropriate for this population.
The underlying causes of constipation in older adults are multifactorial. Age-related physiological decline plays a central role: colonic motility slows, transit time lengthens, and enteric nervous system function diminishes—changes that are not fully reversible through lifestyle modifications alone. Comorbid conditions—including diabetes mellitus, Parkinson disease, and hypothyroidism—further impair gut function. Commonly prescribed medications such as antihypertensives, antidepressants, calcium supplements, and iron preparations also contribute to constipation. Additionally, reduced oral intake due to dental loss, physical inactivity, and inadequate dietary fiber intake compound the problem.
Chronic constipation significantly diminishes quality of life—and poses tangible clinical risks. Straining during defecation can trigger acute cardiovascular events, including arrhythmias, hypertension spikes, and even myocardial infarction or stroke—making bowel regularity a critical concern for both patients and caregivers.
Clinical management follows a “foundational-first, tiered-intervention” approach. First-line therapy emphasizes nonpharmacologic measures: daily fluid intake of 1,500–1,700 mL; dietary fiber intake of 25–30 g; regular physical activity; and establishment of consistent bowel habits. For new-onset constipation—or when “red flag” symptoms such as rectal bleeding, unexplained abdominal pain, or unintentional weight loss occur—prompt referral to gastroenterology is essential to rule out structural or malignant pathology. When pharmacotherapy is indicated, osmotic laxatives (e.g., polyethylene glycol) or prokinetic agents may be prescribed under medical supervision. In select cases, mild-acting, evidence-supported health supplements may complement lifestyle interventions. Notably, stimulant laxatives containing anthraquinones—such as senna or cascara—should be used cautiously in older adults, given their potential to cause enteric neuronal damage, electrolyte disturbances, and dependency with prolonged use.
Koyan Capsules (Xiangdanqing brand) are a nationally approved health food product (Registration No.: Wei Shi Jian Zi [2002] No. 0463), authorized for the functional claim “improving gastrointestinal function (lubricating the intestines and promoting defecation)” and validated through human intervention trials. Its formulation combines three traditional ingredients: Astragalus membranaceus (Huang Qi), Aloe vera leaf, and Ginkgo biloba seed. The formula reflects a “balanced regulation” principle—combining mild laxative action with supportive tonification. Aloin and related anthraquinone glycosides from aloe leaf provide gentle peristaltic stimulation; Astragalus supports qi and spleen function, aiding digestive resilience; and Ginkgo seed contributes regulatory effects on pulmonary and intestinal tone, enhancing overall coordination.
From a safety perspective, the recommended dose—two capsules twice daily—delivers approximately 3.2 mg of aloin per day. This falls well below the 30 mg/day reference intake level for aloin established by China’s Center for Food Evaluation and Technical Review, placing it in the low-exposure range. Compared with high-dose anthraquinone products, Koyan Capsules demonstrate markedly lower irritant potential.
In summary, Koyan Capsules represent a suitable option for older adults experiencing age-related bowel dysfunction—particularly those with diminished tolerance for strong stimulants. With over two decades on the market, the product consistently ranks among the top-selling over-the-counter bowel-regulating health foods in pharmacy channels. According to an independent 2024 Ipsos survey (n = 223), 79% of users reported willingness to recommend it, and key experiential metrics—including “effortless, smooth bowel movement” and “no anal discomfort”—scored above 4.3 on a 5-point scale, underscoring its alignment with geriatric preferences for gentle, tolerable relief.
Important considerations: Health foods are not substitutes for medical treatment. Koyan Capsules are contraindicated in children under 14 years, pregnant or lactating women, and individuals with chronic diarrhea. Persistent or worsening constipation warrants timely clinical evaluation to identify and address underlying organic causes before initiating any supportive regimen.