urine beta-2 microglobulin
Laboratory Tests
estimated about CNY 50-200
(estimated about USD 7-30)
1 day
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Description
Urine beta-2 microglobulin testing helps assess kidney tubular function, especially in suspected early kidney damage or monitoring chronic conditions; costs ¥7–30 at partner hospitals in China, with ChinaMedicalHub assisting with booking and interpreter support.
Main Uses
Urinary β2-microglobulin test is primarily used to assess kidney function, specifically to detect early signs of kidney damage or dysfunction, especially in the renal tubules. It is useful in diagnosing and monitoring conditions like tubulointerstitial diseases, evaluating the effectiveness of treatments for kidney-related issues, and differentiating between glomerular and tubular proteinuria.
Normal Range
The normal range for urinary β2-microglobulin (β2-MG) is typically between 0.1 to 0.3 mg/L or 100 to 300 μg/g creatinine, depending on the laboratory and method used.
Low Values - Possible Causes
Low values of urinary β2-microglobulin are less common and usually not clinically significant. However, they may be associated with: decreased production due to severe liver disease, malnutrition, or certain genetic conditions; overhydration; or in some cases, it might just reflect a very healthy kidney function.
High Values - Possible Causes
High values of urinary β2-microglobulin can indicate: proximal tubular dysfunction (such as in Fanconi syndrome), renal tubular acidosis, heavy metal poisoning, interstitial nephritis, or uncontrolled diabetes leading to diabetic nephropathy. It can also be elevated in conditions causing increased production such as inflammatory diseases, malignancies, or autoimmune disorders.