Urine alpha-1-microglobulin
Laboratory Tests
estimated about CNY 50-200
(estimated about USD 8-30)
24 hr
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Description
Urine alpha-1-microglobulin testing helps detect early kidney tubular damage, especially in diabetes or hypertension; costs ¥8–30 at partner hospitals in China, with ChinaMedicalHub assisting with booking and interpreter support.
Main Uses
Urinary α1-microglobulin testing is primarily used to assess kidney function, specifically to detect early signs of tubular damage. It is also useful in monitoring the progression of kidney diseases, evaluating the effectiveness of treatments, and as a marker for renal involvement in systemic diseases such as diabetes and hypertension.
Normal Range
The normal range for urinary α1-microglobulin (α1-MG) is typically between 0-20 mg/L. This value can vary slightly depending on the laboratory and the specific method used for measurement.
Low Values - Possible Causes
Low values of urinary α1-microglobulin are less common and generally not clinically significant. However, they may be observed in cases of severe protein malnutrition, liver failure, or certain genetic conditions affecting protein synthesis.
High Values - Possible Causes
High values of urinary α1-microglobulin can indicate kidney damage, particularly tubular dysfunction. Common causes include diabetic nephropathy, glomerulonephritis, interstitial nephritis, heavy metal poisoning, and post-renal transplant complications.