Thyroid Peroxidase Antibodies
Laboratory Tests
estimated about CNY 100-300
(estimated about USD 15-45)
24 hr
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Description
Thyroid peroxidase antibodies (TPOAb) testing helps diagnose autoimmune thyroid conditions like Hashimoto’s or Graves’ disease; in China, the test costs ¥15–45 and ChinaMedicalHub can assist with hospital booking and interpreter support.
Main Uses
The primary purpose of the TPOAb test is to diagnose and monitor autoimmune thyroid diseases, such as Hashimoto's thyroiditis and Graves' disease. It is also used to evaluate the cause of hypothyroidism or hyperthyroidism, especially when these conditions are suspected to have an autoimmune origin. Additionally, it can help in assessing the risk of developing postpartum thyroiditis in pregnant women with a history of thyroid issues.
Normal Range
The normal range for Thyroid Peroxidase Antibodies (TPOAb) is typically less than 35 IU/mL, but this can vary slightly depending on the laboratory and the specific testing method used. Always refer to the reference range provided by the lab conducting the test.
Low Values - Possible Causes
Low levels of TPOAb are generally not a concern as they indicate an absence or minimal presence of antibodies against thyroid peroxidase. This is usually seen in individuals without autoimmune thyroid diseases. Low values do not typically require further investigation unless there's a clinical suspicion of another condition.
High Values - Possible Causes
High levels of TPOAb may be caused by: 1. Hashimoto's thyroiditis, 2. Graves' disease, 3. Postpartum thyroiditis, 4. Silent thyroiditis, 5. Other autoimmune conditions that might affect the thyroid gland.