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Electrooculography

Eye Care estimated about CNY 400-750

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Description

A diagnostic test that measures the corneo-retinal standing potential to assess retinal function, particularly the retinal pigment epithelium, using skin electrodes placed around the eyes.

Main Uses

EOG is primarily used to assess retinal pigment epithelium (RPE) and photoreceptor outer segment function; it is a key diagnostic test for Best disease and other RPE-related dystrophies; aids in differentiating retinal from optic nerve disorders; evaluates generalized retinal dysfunction in inherited retinal diseases; monitors disease progression in chronic retinal conditions; and supports electrophysiological diagnosis when combined with ERG and VEP.

Normal Range

The normal EOG Arden ratio (light peak/dark trough amplitude) is ≥1.8 (180%); values between 1.6–1.79 are considered borderline; <1.6 indicates abnormality. Absolute amplitude values vary by equipment and age but typically: dark trough = 50–150 μV, light peak = 100–300 μV. Interocular asymmetry should be <20%.

Low Values - Possible Causes

Retinitis pigmentosa, Best vitelliform macular dystrophy, advanced age-related macular degeneration (geographic atrophy), chronic retinal detachment, severe vitamin A deficiency, long-standing diabetes with retinal pigment epithelium dysfunction.

High Values - Possible Causes

Rare; may occur in early-stage retinal dystrophies with transient hyperactivity (e.g., some cases of congenital stationary night blindness), acute central serous chorioretinopathy (transient elevation), artifact due to excessive eye movement or poor electrode contact, hyperthyroidism (theoretical association, not well-established), pharmacologic stimulation (e.g., recent caffeine or sympathomimetic use).

electrooculography retinal pigment epithelium function test Arden ratio

estimated about CNY 400-750