Alpha-fetoprotein Test
Laboratory Tests
estimated about CNY 200-500
(estimated about USD 30-70)
30 min
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Description
The alpha-fetoprotein (AFP) test screens for liver cancer, certain germ cell tumors, and neural tube defects during pregnancy; in China, it costs ¥200–¥500 and ChinaMedicalHub helps coordinate hospital appointments with interpreter support.
Main Uses
Alpha-Fetoprotein (AFP) testing is primarily used for: 1. Screening and monitoring for hepatocellular carcinoma, especially in patients with chronic liver diseases like hepatitis B or C, 2. Diagnosing and monitoring germ cell tumors, 3. As part of prenatal screening to detect potential birth defects such as neural tube defects or abdominal wall defects, 4. Assessing liver function and damage in certain liver diseases.
Normal Range
The normal range for Alpha-Fetoprotein (AFP) in adults is typically less than 10 ng/mL. For pregnant women, the levels can vary significantly depending on the gestational age, but generally, a level of less than 40 ng/mL is considered within the normal range during the second trimester.
Low Values - Possible Causes
Low AFP values are not commonly a cause for concern and do not usually indicate any specific health issues. However, in some cases, very low levels might be associated with Down syndrome in prenatal screening, or could simply reflect individual biological variation.
High Values - Possible Causes
High AFP values can be caused by several conditions including: 1. Hepatocellular carcinoma (liver cancer), 2. Germ cell tumors (such as testicular or ovarian cancers), 3. Liver cirrhosis or hepatitis, 4. Ataxia telangiectasia, 5. During pregnancy, high levels may indicate neural tube defects or multiple pregnancies.