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repetitive transcranial magnetic stimulation

Rehabilitation estimated about CNY 300-800

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Description

A non-invasive neuromodulation technique using rapidly changing magnetic fields to induce electrical currents in targeted cortical brain regions, primarily used for treatment-resistant depression and other neuropsychiatric disorders.

Main Uses

Primary clinical uses include: FDA-cleared treatment for major depressive disorder (MDD) in adults who have failed ≥1 antidepressant trial; adjunctive treatment for obsessive-compulsive disorder (OCD); investigational/expanded-use applications in anxiety disorders, PTSD, chronic pain (e.g., fibromyalgia, neuropathic pain), smoking cessation, stroke rehabilitation (motor recovery), and negative symptoms of schizophrenia. Used in outpatient neurology and psychiatry settings under physician supervision.

Normal Range

rTMS is not a diagnostic laboratory test with quantitative 'values' or numerical reference ranges; it is a non-invasive neuromodulation therapy. Parameters such as motor threshold (MT), stimulation intensity (% of MT), frequency (Hz), pulse number, train duration, and inter-train interval are individually titrated during clinical setup. Typical therapeutic intensities range from 80–120% of resting motor threshold (RMT); common frequencies include 1 Hz (inhibitory) and 10 Hz (excitatory); standard protocols involve 30–60 trains per session, each lasting 4–10 seconds, with 20–60 second inter-train intervals.

Low Values - Possible Causes

Low stimulation efficacy may result from: (1) subthreshold dosing (intensity <80% RMT), (2) coil misplacement or poor scalp contact, (3) elevated motor threshold due to medication (e.g., benzodiazepines, anticonvulsants), (4) anatomical factors (e.g., increased scalp-to-cortex distance from skull thickness or atrophy), (5) technical issues (e.g., device calibration error or coil degradation).

High Values - Possible Causes

Excessively high or adverse stimulation effects may arise from: (1) suprathreshold intensity (>120% RMT) without titration, (2) excessive frequency or total pulse count (e.g., >3000 pulses/session), (3) inadequate inter-train intervals leading to cortical hyperexcitability, (4) pre-existing hyperexcitable states (e.g., untreated epilepsy, recent sleep deprivation), (5) concurrent use of serotonergic or stimulant medications lowering seizure threshold.

transcranial magnetic stimulation repetitive TMS neuromodulation therapy

estimated about CNY 300-800