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Optical Coherence Tomography

Eye Care estimated about CNY 300-600
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Description

A non-invasive imaging test that uses light waves to take cross-section pictures of the retina, enabling detailed visualization of retinal layers and aiding in diagnosis and management of ocular diseases.

Main Uses

Primary clinical uses include early detection and longitudinal monitoring of glaucoma (via RNFL and GCIPL analysis), diagnosis and management of retinal diseases (e.g., diabetic retinopathy, age-related macular degeneration, macular holes, epiretinal membranes), assessment of optic nerve head morphology, evaluation of vitreoretinal interface disorders, neuro-ophthalmologic evaluation (e.g., optic neuritis, multiple sclerosis), and guiding intravitreal therapy decisions (e.g., anti-VEGF treatment for macular edema).

Normal Range

OCT is an imaging modality, not a quantitative blood or biochemical test; therefore, it does not have numerical 'normal ranges' in the conventional sense. Instead, interpretation relies on qualitative and semi-quantitative structural metrics: retinal nerve fiber layer (RNFL) thickness (normal: 70–120 µm, varies by age/location), macular ganglion cell-inner plexiform layer (GCIPL) thickness (normal: 65–95 µm), central subfield thickness (CST) in healthy eyes (normal: 200–270 µm), and choroidal thickness (normal: 200–350 µm, highly variable by age, ethnicity, refractive error). Normative databases embedded in OCT devices provide age- and location-matched percentile comparisons (e.g., values <5th percentile flagged as abnormal).

Low Values - Possible Causes

Retinal atrophy (e.g., advanced glaucoma, retinitis pigmentosa), optic nerve degeneration (e.g., optic neuritis sequelae, hereditary optic neuropathies), macular telangiectasia (MacTel), chronic diabetic macular ischemia, severe age-related macular degeneration (geographic atrophy), and post-surgical or post-traumatic retinal thinning.

High Values - Possible Causes

Macular edema (e.g., diabetic macular edema, retinal vein occlusion, uveitic cystoid macular edema), vitreomacular traction syndrome, epiretinal membrane (ERM)-induced retinal thickening, choroidal neovascularization (CNV) with subretinal fluid, and inflammatory retinal infiltration (e.g., sarcoidosis, syphilitic chorioretinitis).
estimated about CNY 300-600
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