Optical Coherence Tomography Angiography
Eye Care
estimated about CNY 450-800
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Description
A non-invasive imaging technique that visualizes retinal and choroidal microvasculature using motion contrast from flowing blood without dye injection.
Main Uses
Non-invasive visualization and quantitative assessment of retinal and choroidal microvasculature; early detection and monitoring of diabetic retinopathy, glaucoma, age-related macular degeneration, retinal vascular occlusions, and inherited retinal diseases; evaluation of foveal avascular zone (FAZ) morphology and integrity; differentiation of neovascularization (e.g., type 1 vs. type 2 MNV); treatment response assessment (e.g., anti-VEGF therapy); research applications in neuro-ophthalmology and systemic disease biomarkers (e.g., Alzheimer’s, hypertension).
Normal Range
OCTA does not yield scalar 'values' with blood tests. Instead, it produces qualitative and semi-quantitative metrics (e.g., vessel density [%], foveal avascular zone [FAZ] area [mm²], FAZ circularity, perfusion density [%], choriocapillaris flow deficit area [%]). Normal ranges vary by device (e.g., Zeiss AngioPlex, Optovue RTVue XR Avanti), scan protocol (3×3 mm, 6×6 mm),ficial capillary plexus [SCP], deep capillary plexus [DCP], choriocapillaris), and age. Example typical values in healthy adults: SCP vessel density = 45–55%; DCP vessel density = 50–60%; FAZ area = 0.25–0.35 mm²; FAZ circularity = 0.70–0.90; choriocapillaris perfusion density = 65–75%.
Low Values - Possible Causes
Diabetic retinopathy (capillary non-perfusion), retinal vein occlusion (ischemia), glaucomatous optic neuropathy (reduced peripapillary vessel density), age-related macular degeneration (geographic atrophy, choroidal flow deficits), retinitis pigmentosa (progressive microvascular attenuation), hypertensive retinopathy (arteriolar narrowing and capillary dropout).
High Values - Possible Causes
OCTA does not produce clinically meaningful 'high' quantitative values in the conventional sense; apparent 'increased' signal is typically artifactual — e.g., motion artifacts, projection artifacts (especially in DCP/choriocapillaris), segmentation errors, vitreous opacities, or excessive image averaging. True pathologic hyperperfusion is exceedingly rare and not reliably quantified by current OCTA; conditions like inflammatory vasculitis may show irregular flow but not globally elevated vessel density.
estimated about CNY 450-800
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