N-Acetyl-beta-D-glucosaminidase (NAG)
Laboratory Tests
estimated about CNY 50-200
(estimated about USD 7-30)
1 hr
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Description
N-Acetyl-beta-D-glucosaminidase (NAG) urine test helps detect early kidney tubular damage, often ordered for diabetes or hypertension monitoring in China; reference cost ¥7–30 with hospital booking support via ChinaMedicalHub.
Main Uses
The primary purpose of measuring N-Acetyl-β-D-Glucosaminidase (NAG) in urine is to assess early signs of kidney damage, particularly in the proximal tubules. It is useful in diagnosing and monitoring various forms of nephropathy, including drug-induced, diabetic, and hypertensive nephropathies. Additionally, it helps in evaluating the effectiveness of treatments aimed at preserving kidney function.
Normal Range
The normal range for N-Acetyl-β-D-Glucosaminidase (NAG) in urine is typically between 0.3 and 2.5 U/L, though this can vary slightly depending on the laboratory and the specific method used for measurement.
Low Values - Possible Causes
Low values of NAG in urine are less commonly a concern but may be associated with: decreased renal tubular function, certain medications that reduce enzyme activity, or very rarely, genetic deficiencies affecting NAG production.
High Values - Possible Causes
High values of NAG in urine can indicate: acute kidney injury, chronic kidney disease, interstitial nephritis, heavy metal toxicity, or urinary tract infections. These conditions lead to increased release of NAG from damaged renal tubules into the urine.