角膜染色（荧光素钠）
眼科项目
≈ ¥20-50
(≈ $3-7)
大约15-30分钟
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项目介绍
角膜染色（荧光素钠）在一般公立医院参考费用约¥15-40，三甲医院参考费用约¥20-50，常用于相关诊断评估与就医安排，费用随医院及地区有所差异。
主要用途
Corneal fluorescein staining is primarily used to detect and assess the severity, location, and pattern of corneal epithelial defects. Key clinical applications include: evaluating tear film stability and ocular surface health in dry eye syndrome; diagnosing corneal injuries (abrasions, foreign body removal sites); monitoring healing after refractive surgery (e.g., LASIK, SMILE); identifying infectious or inflammatory keratopathies (e.g., dendritic ulcers in herpes simplex); and assessing neurotrophic or exposure-related epithelial breakdown.
正常值范围
No staining (i.e., negative result) is normal: intact corneal epithelium shows no uptake of sodium fluorescein dye under cobalt-blue light. A normal test reveals a smooth, continuous, non-fluorescent corneal surface with no punctate, dendritic, geographic, or diffuse staining patterns.
偏低可能原因
Low or absent staining is not clinically pathological—it reflects epithelial integrity. However, 'low staining' in practice may indicate: (1) inadequate dye application or rinsing; (2) insufficient cobalt-blue illumination or improper filter use; (3) examiner error (e.g., misinterpretation of subtle early defects); (4) overly rapid tear turnover washing away dye before observation; (5) use of outdated or degraded fluorescein strips/solution.
偏高可能原因
Abnormal (positive) staining indicates epithelial disruption and includes: (1) dry eye disease (aqueous-deficient or evaporative); (2) corneal abrasion or trauma; (3) infectious keratitis (bacterial, viral e.g., HSV dendritic ulcers, fungal); (4) neurotrophic keratopathy; (5) exposure keratopathy (e.g., lagophthalmos, facial nerve palsy).