角膜知觉检查（Cochet-Bonnet角膜知觉计）
眼科项目
≈ ¥20-50
(≈ $3-7)
大约15-30分钟
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项目介绍
角膜知觉检查（Cochet-Bonnet角膜知觉计）在一般公立医院参考费用约¥15-40，三甲医院参考费用约¥20-50，常用于相关诊断评估与就医安排，费用随医院及地区有所差异。
主要用途
Assessing trigeminal nerve (ophthalmic division, V1) function; diagnosing neurotrophic keratopathy; evaluating risk of corneal epithelial breakdown pre- and post-refractive surgery (e.g., LASIK, SMILE); monitoring progression in systemic neuropathies (e.g., diabetes, sarcoidosis); guiding management of persistent corneal ulcers or recurrent erosions.
正常值范围
Normal corneal sensation is typically 40–60 mm filament length (measured using Cochet-Bonnet esthesiometer), corresponding to a pressure threshold of approximately 0.8–2.0 g/mm²; values ≥45 mm generally indicate intact trigeminal (V1) innervation and normal protective reflexes.
偏低可能原因
Trigeminal neuropathy (e.g., herpes zoster ophthalmicus), diabetic peripheral neuropathy, leprosy (Hansen’s disease), post-surgical nerve damage (e.g., after refractive or cataract surgery), chronic dry eye with neurotrophic keratopathy.
偏高可能原因
True 'high' corneal sensation is not clinically meaningful or measurable with Cochet-Bonnet esthesiometer; apparent hyperesthesia is usually artifactual (e.g., patient anxiety, eyelid spasm, examiner technique error, or misinterpretation of response); no validated pathological condition causes objectively increased corneal sensation — thus 'high values' are not recognized as a true abnormality and reflect test limitation or false-positive response.